Soma Dol T 450mg is a potent blend of carisoprodol and tapentadol.
Carisoprodol is used in treating short term muscle pain and muscle skeletal disorders which includes back pain. It is meant to be used along with rest, physical therapy and other measure to relax muscles after strains, sprains and muscle injuries. It is indicated for the relief of discomfort associated with acute, painful musculoskeletal conditions in adults.
Use is only approved for up to three weeks.
Tapentadol is similar to tramadol in its dual mechanism of action. Namely, its ability to activate the mu opioid receptor and inhibit the reuptake of norepinephrine.
It is not a pro drug and therefore does not rely on metabolism to produce its therapeutic effects; this makes it a useful moderate potency analgesic option for patients who do not respond adequately to more commonly used opioids due to genetic disposition (poor metabolizers of CYP3A4 and CYP2D6), as well as providing a more consistent dosage-response range among the patient population.
The potency of tapentadol is somewhere between that of tramadol and morphine, with an analgesic efficacy comparable to that of oxycodone despite a lower incidence of side effects. It is generally regarded as a moderately strong opioid.
